Endocarditis, kunstklep - Vergroenende streptokokken (viridans/mitis/gallolyticus)
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: benzylpenicilline iv loading dose 2million. IU, 12million. IU continuous per 24 hours 6 weeks |
|
|
Priority: 1st choice alternative |
Medication: benzylpenicilline iv 2million. IU 6dd 6 weeks |
|
|
Priority: 2nd choice |
Medication: ceftriaxon iv 2g 1dd 6 weeks |
Remarks:
Bij niet-ernstige penicillineallergie |
|
Priority: 2nd choice alternative |
Medication: vancomycine iv continuous per 24 hours 6 weeks |
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: benzylpenicilline iv loading dose 3million. IU, 18million. IU continuous per 24 hours 6 weeks +
gentamicine iv 3mg/kg 1dd 2 weeks |
Remarks:
Voor gentamicine zie algemene opmerkingen |
|
Priority: 1st choice alternative |
Medication: benzylpenicilline iv 3million. IU 6dd 6 weeks +
gentamicine iv 3mg/kg 1dd 2 weeks |
Remarks:
Voor gentamicine zie algemene opmerkingen |
|
Priority: 2nd choice |
Medication: ceftriaxon iv 2g 1dd 6 weeks +
gentamicine iv 3mg/kg 1dd 2 weeks |
|
|
Priority: 2nd choice alternative |
Medication: vancomycine iv continuous per 24 hours 6 weeks |
Sources
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
Menu position
Metadata
Swab vid: G-144228.10
Updated: 06/23/2025 - 14:58
Status: Published
General comments
Gentamicine
Indien gentamicine vaker dan één keer wordt toegediend:
Bij gebruik van gentamicine moeten spiegelbepalingen worden verricht.
Bij obesitas (BMI≥30 kg/m2): om toxiciteit (m.n. nefro- en neurotoxiciteit) bij obese patiënten te voorkomen, doseer op basis van het adjusted body weight
Vancomycine
Voor dosering vancomycine en spiegelbepalingen zie Vancomycine dosering en TDM