Endocarditis, kunstklep - Staphylococcus aureus of CNS
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: flucloxacilline iv 12g continuous per 24 hours 6 weeks +
rifampicine po 1200mg/24h 2 doses 6 weeks +
gentamicine iv 3mg/kg/24h 1dd 2 weeks |
|
|
Priority: 2nd choice |
Medication: cefazoline iv 6g continuous per 24 hours 6 weeks +
rifampicine po 1200mg/24h 2 doses 6 weeks +
gentamicine iv 3mg/kg/24h 1dd 2 weeks |
Remarks:
Bij niet-ernstige beta-lactam allergie |
|
Priority: 2nd choice alternative |
Medication: vancomycine iv continuous per 24 hours 6 weeks +
rifampicine po 1200mg/24h 2 doses 6 weeks +
gentamicine iv 3mg/kg/24h 1dd 2 weeks |
Remarks:
Bij ernstige beta-lactam allergie Bij vancomycine volg protocol: TDM vancomycine doseringen Vancomycine streefspiegel: 20-25 mg/L |
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: vancomycine iv continuous per 24 hours 6 weeks +
rifampicine po 1200mg/24h 2 doses 6 weeks +
gentamicine iv 3mg/kg/24h 1dd 2 weeks |
Remarks:
Bij vancomycine volg protocol: TDM vancomycine doseringen Vancomycine streefspiegel: 20-25 mg/L Als vancomycine niet gegeven kan worden overleg met MMB |
Sources
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
Menu position
Metadata
Swab vid: G-144419.8
Updated: 09/26/2022 - 10:04
Status: Published
General comments
Bij gebruik van gentamicine moeten spiegelbepalingen worden verricht.
Bij toxiciteit stop gentamicine