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Endocarditis, natieve klep - empirische therapie

Advices

≥ 18 years

Indications: Subacute presentatie

Priority Medication Remarks
Priority:
1st choice
Medication:

amoxicilline iv 12g continuous per 24 hours

+

ceftriaxon 2000mg 2dd

Priority:
2nd choice
Medication:

vancomycine iv continuous per 24 hours

ceftriaxon 2000mg 1dd

Remarks:

Bij niet-ernstige penicilline allergie

Bij vancomycine volg protocol: TDM vancomycine doseringen

Plateauconcentratie: 20-25 mg/L

≥ 18 years

Indications: Acute presentatie

Priority Medication Remarks
Priority:
1st choice
Medication:

flucloxacilline iv 12g continuous per 24 hours

Priority:
2nd choice
Medication:

cefazoline iv 6g continuous per 24 hours

Remarks:

Bij niet-ernstige penicilline allergie

Priority:
2nd choice alternative
Medication:

vancomycine iv continuous per 24 hours

Remarks:

Bij ernstige beta-lactam allergie

Bij vancomycine volg protocol: TDM vancomycine doseringen

Plateauconcentratie: 20-25 mg/L

General comments

Voor dosering vancomycine en spiegelbepalingen: Vancomycine dosering en TDM.

Empirische therapie aanpassen op geleide kweek, zie SWAB richtlijn

 

 

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-500661.3
Updated: 10/07/2022 - 16:14
Status: Published