Endocarditis, natieve klep - empirische therapie
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: amoxicilline iv loading dose 2g, 12g continuous per 24 hours +
ceftriaxon 2g 2dd |
|
|
Priority: 2nd choice |
Medication: vancomycine iv continuous per 24 hours +
ceftriaxon 2g 1dd |
Remarks:
Bij niet-ernstige penicilline allergie Bij vancomycine volg protocol: TDM vancomycine doseringen Plateauconcentratie: 20-25 mg/L |
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: flucloxacilline iv loading dose 2g, 12g continuous per 24 hours |
|
|
Priority: 1st choice alternative |
Medication: flucloxacilline iv 2g 6dd |
|
|
Priority: 2nd choice |
Medication: cefazoline iv loading dose 2g, 6g continuous per 24 hours |
Remarks:
Bij niet-ernstige penicilline allergie |
|
Priority: 2nd choice alternative |
Medication: vancomycine iv continuous per 24 hours |
Remarks:
Bij ernstige beta-lactam allergie Bij vancomycine volg protocol: TDM vancomycine doseringen Plateauconcentratie: 20-25 mg/L |
Sources
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
Menu position
Metadata
Swab vid: G-500661.4
Updated: 06/11/2025 - 17:25
Status: Published
General comments
Voor dosering vancomycine en spiegelbepalingen: Vancomycine dosering en TDM.
Empirische therapie aanpassen op geleide kweek, zie SWAB richtlijn