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Endocarditis, kunstklep - Cutibacterium (Propionibacterium) spp.

Advices

≥ 18 years
Priority Medication Remarks
Priority:
1st choice
Medication:

benzylpenicilline iv loading dose 2million. IU, 12million. IU continuous per 24 hours 6 weeks

Priority:
1st choice alternative
Medication:

benzylpenicilline iv 2million. IU 6dd 6 weeks

Priority:
2nd choice
Medication:

ceftriaxon iv 2000/2000mg 2dd 6 weeks

Remarks:

Bij niet-ernstige penicillineallergie

Priority:
2nd choice alternative
Medication:

vancomycine iv continuous per 24 hours 6 weeks

Remarks:

Bij ernstige bètalactamallergie

Voor vancomycine zie algemene opmerkingen

Plateauconcentratie: 20-25 mg/L

General comments

Overweeg toevoegen van rifampicine 1200 mg/dag bij specifieke casuïstiek 

Vancomycine 
Voor dosering vancomycine en spiegelbepalingen zie Vancomycine dosering en TDM

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-500939.2
Updated: 08/18/2025 - 13:18
Status: Published