Home Medication antibacterial
Home Medication antibacterial

aztreonam/avibactam

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DF - Monobactams -> J01DF01 - Aztreonam
Administration category: Limited Medicine group: antibacterial Brand name: Emblaveo

Standard dosages

≥ 18 years
Weight ROA Load Dosage
ROA:
 iv 		Load:
 1500mg/500mg 		Dosage:
 6000/2000mg
ROA:
 iv 		Load:
 - 		Dosage:
 1500/500mg 4 dd
Comments:

Oplaaddosis 1500/500 mg in 1 uur. Daarna continue infuus/24 uur.

Kidney function

Notes GFR general:

Continue

  • kreatinineklaring >50 ml/min: OD 1500/500 mg in 1 uur, 6000/2000 mg/24 uur
  • kreatinineklaring 30-50 ml/min: OD 1500/500 mg in 1 uur, 3000/1000 mg/24 uur
  • kreatinineklaring 15-30 ml/min: OD 1500/500 mg in 1 uur, 2000/667 mg/24 uur
  • intermitterende hemodialyse: OD 1500/500 mg in 1 uur, 1500/500 mg/24 uur
  • kreatinineklaring kleiner dan ≤15 ml/min en geen nierfunctievervangende therapie: gecontra-indiceerd

Intermitterend

  • kreatinineklaring >50 ml/min: 4dd 1500/500 mg in 3 uur

  • kreatinineklaring 30-50 ml/min: 4dd 750/250 mg in 3 uur

  • kreatinineklaring 15-30 ml/min: 3dd 675/225 mg in 3 uur

  • Bij intermitterende hemodialyse: 2dd 675/225 mg in 3 uur

  • kreatinineklaring kleiner dan ≤15 ml/min en geen nierfunctievervangende therapie: gecontra-indiceerd
Renal elimination: 75-80%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: geen gegevens bekend

Hemo dialysis: zie advies bij kreatinineklaring kleiner dan 15 ml/min

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-502502.3
Updated: 01/30/2025 - 16:21
Status: Published

Menu position